double-stranded rna viral infection in tehran trichomonas vaginalis isolates.

background : trichomonas vaginalis is a pathogenic protozoon and may be contaminated with dsrna virus called trichomonas vaginalis virus (tvv). the viral infection is an important factor for its patho-genesis and sensitivity to metronidazole. the presence of tvv is associated with qualitative and quantitative expression of cysteine proteinases and surface immunogenic; p270. the purpose of this study was to determine tvv frequency in t. vaginalis clinical isolates in tehran, iran. methods: the 46 t. vaginalis isolates were collected from tehran province and cultured in tyi-s-33 culture medium. viral rna was extracted and rt-pcr was done. results: of 46 t. vaginalis isolates, 8 isolates (17.39%) were infected with tvv-1. there was not any association between patient age and tvv- infected t. vaginalis . there were 17.39% viral infection in t. vaginalis isolates which was lower than that reported by other researchers. conclusion: this is the first report on t. vaginalis isolates infection by tvv-1 in iran.